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Sandra Kurtin, PhD, ANP-C, AOCN, of The University of Arizona Cancer Center, discusses the challenges for advanced practitioners treating patients with hematologic malignancies who are at high risk for COVID-19 infection. However, the ability to successfully detect SARS-CoV-2 in these patients remains unknown, with a strikingly high false-negative rate, and data regarding their clinical course, treatment, and outcomes is sparse (Abstract 313).