Current Issue
VOL 10 • NO 2 MAR 2019
This issue's cover illustration depicts a patient receiving an IV treatment of single-valent virus-specific T-cell therapy with antigen-specific T cells. The T cells are activated by exposure to adenovirus (shown over the image). Viral infections remain a major complication after hematopoietic stem cell transplant. Artwork by Alexandra Webber Baker, © 2019, DNA Illustrations, Inc., Asheville, North Carolina.EditorialPamela Hallquist Viale, RN, MS, CNS, ANPThe American Cancer Society estimates 101,420 new cases of colon cancer and 44,180 new cases of rectal cancer in the United States this year (American Cancer Society, 2019). Colorectal cancer remains the third leading cause of death from cancer in both sexes, with approximately 51,020 deaths expe...
Quality ImprovementSheila A. Kenny,(1) MSN, RN, ANP-BC, Karen Collum,(1) DNP, RN, OCN®, Catherine A. Featherstone,(1) MSN, RN, FNP-BC, Azeez Farooki,(1,2) MD, and Ann Jakubowski,(1,2) PhD, MDPatients undergoing hematopoietic stem cell transplant (HSCT) are at high risk for vitamin D deficiency before and after transplant, and more so than the general population (Urbain, Ihorst, Biesalski, & Bertz, 2012; Wallace et al., 2015). The prevalence of vitamin D deficiency has been report...
Review ArticleHeidi Z. Simmons, MSN, RN, FNP-C, Angela F. Bazzell, DNP, RN, FNP-BC, AOCNP®, and Joyce E. Dains, DrPH, JD, RN, FNP-BCAllogeneic hematopoietic stem cell transplant (HSCT) has become the standard of care in treating many hematologic malignancies and other immunodeficiency disorders, with over 1 million HSCTs performed in the past 50 years (Gratwohl et al., 2015; Singh & McGuirk, 2016). According to the Center...
Continuing EducationAdvances in HER2-Positive Breast Cancer: Novel Therapies and Adverse Event Management
Access the certified article here.
A continuing education activity for nurse practitioners, PAs, clinical nurse specialists, advanced degree nurses, oncology and hematology nurses, pharmacists, and physicians...
Grand RoundsReshma Mahtani, DO, and Lisa Hineman, MS, AOCN®, PHN, ANP-CBased on data from the American Cancer Society (ACS), survival is improving for patients with breast cancer (BC), largely because of earlier detection and improved treatment modalities (ACS, 2018). Notwithstanding these improvements, nearly 42,000 women died from metastatic breast cancer (MBC) in...
Grand RoundsLynn Weatherby, RN, BSN, OCN®, and Lynne Brophy, MSN, RN-BC, APRN-CNS, AOCN® Chemotherapy-induced alopecia (CIA) is a frequent side effect of systemic antineoplastic therapy for cancer. It occurs when chemotherapy drugs such as taxanes, anthracyclines, and alkylating agents target rapidly dividing keratinocytes cells, damaging the hair follicle and resulting in CIA (Paus,...
Prescriber's CornerSarah E. Caulfield, PharmD, BCOP, Christine C. Davis, PharmD, BCOP, and Kristina F. Byers, PharmD, BCOPBreast cancer is the most frequently diagnosed cancer in women globally. In 2019, an estimated 268,600 new cases will be diagnosed in the United States. The rate of newly diagnosed cases has largely remained the same over the past several years, with death rates falling an average of 1.8% each ye...
Tools and TechnologyKristin K. Ownby, PhD, RN, ACHPN, AOCN®, ANP-BCFor many patients, the cancer care journey is fraught with distress, beginning with initial diagnosis, through the treatment decision-making process and cancer treatment, and into survivorship. Uncertainty about the future is commonly present throughout the cancer trajectory (Bultz & Holland,...
Diagnostic SnapshotRashida Taher, MPH, PA-C, and Sandra E. Kurtin, PhD, ANP-C, AOCN®HISTORY
Mr. C, a 63-year-old Cape Verdean male, was referred to the hematology/oncology office for evaluation of eosinophilia in May 2017. The eosinophilia was first documented in December 2003 by his primary care provider. In March 2005, Mr. C underwent colonoscopy for mild rectal bleeding and w...
