Current Issue


VOL 13 NO 1 • JAN/FEB 2022


This issue’s cover illustration depicts breakthrough cancer pain, a transient exacerbation of pain that occurs within the context of stable and adequately controlled background pain. The dotted line indicates the level for around-the-clock analgesia to control baseline pain. The red spikes indicate the areas of breakthrough pain. The final spike of pain is shown being controlled by a transmucosal fentanyl application. The circuit board represents the use of electronic algorithms to integrate patient empowerment by shared decision-making. Artwork by Alexandra Webber Baker © 2022, DNA Illustrations, Inc., Asheville, North Carolina.


Editorial

Resolving Not to Make New Year’s Resolutions

Beth Faiman, PhD, MSN, APRN-BC, AOCN®, FAAN

Recently, a colleague and I aimed to discuss something other than the surge in the number of COVID-19 cases that have affected the country. Advanced practitioners (APs) across the nation are facing unpredictable and stressful situations such as critically short staffing and decision-making challe...


Research and Scholarship

Shared Decision-Making in Managing Breakthrough Cancer Pain in Patients With Advanced Cancer

Jeannine M. Brant,(1) PhD, APRN, AOCN®, FAAN, Debra Wujcik,(2) PhD, RN, FAAN, William N. Dudley,(3) PhD, Alison Petok,(4) MSW, LSW, Brooke Worster,(4) MD, Diane Jones,(1) MSN, NP, Kim Bosket,(1) RN, BSN, OCN®, Christian Brady,(1) MSN, AGNP, APRN, and Carrie Tompkins Stricker,(4) PhD, RN, ANP-BC

Pain is a significant problem in patients with cancer. A meta-analysis of 22 studies indicates that pain is prevalent in 55.0% of patients undergoing active anticancer treatment and in 66.4% of patients with advanced, metastatic, or end-stage disease. Pain is uncontrolled and rated as moderate to...


Research and Scholarship

General and Unique Communication Skills Challenges for Advanced Practice Providers: A Mixed-Methods Study

Deborah Stein,(1) ACNP-BC, Kerry Cannity,(2) PhD, Richard Weiner,(1) NP, Shira Hichenberg,(1) Angelina Leon-Nastasi,(1) Smita Banerjee,(1) PhD, and Patricia Parker,(1) PhD

Advanced practice providers (APPs) play an increasing role in the United States health-care system, and they are often on the front lines of patient care in ambulatory, inpatient, and specialty care settings (Auerbach et al., 2018; Pastores et al., 2019). Advanced practice providers are independe...


Review Article

Emerging Treatment Options for Advanced or Recurrent Endometrial Cancer

Kimberly Halla, FNP-C

Endometrial cancer (EC) is the most common gynecologic malignancy in the United States, with an estimated 65,950 new cases and 12,550 deaths in 2022 (American Cancer Society, 2022). Over the past decade, the incidence has increased by about 1% per year, which is thought to be related to longer li...


Review Article

Antibiotic Therapy and Gastrointestinal Graft-Versus-Host Disease in the Allogeneic Stem Cell Transplantation Population

Jessica Thomas, MSN, APRN, FNP-C, AOCNP®, Christi Bowe, MSN, APRN, ANP-C, and Joyce E. Dains, DrPH, JD, APRN, FNP-BC, FNAP, FAANP

Hematopoietic stem cell transplantation (HSCT) is a treatment option for many individuals who have been diagnosed with cancers such as leukemia, lymphoma, and myeloma. In particular, allogeneic stem cell transplantations (aSCTs) may be associated with long-term sequelae that can affect an individ...


Grand Rounds

Uterine Leiomyosarcoma

Katherine L. Byar,(1) MSN, APN, BC, BMTCN®, and Tricia Fredericks,(2) MD, MPH

CASE STUDY LM is a 51-year-old African American female (gravida 5, para 5) who presented to her primary care provider with complaints of postmenopausal bleeding for 3 days and associated pelvic pain radiating to the left hip. An ultrasound revealed an enlarged uterus (9.9 × 6.1 × 5.6 cm) with mul...


Prescriber's Corner

Belantamab Mafodotin-blmf: A Novel Antibody-Drug Conjugate for Treatment of Patients With Relapsed/Refractory Multiple Myeloma

Emily Behren Ketchum, PharmD, Andrea Clarke, PharmD, BCOP, and Amber B. Clemmons, PharmD, BCOP

Multiple myeloma (MM) is a hematologic malignancy characterized by proliferation of plasma cells with or without production of monoclonal immunoglobulins. The median age of diagnosis is 69 years, with a 5-year survival rate of 54% (American Society of Clinical Oncology, 2021a). Symptomatic multip...


Diagnostic Snapshot

Mysterious Arm Swelling in a Patient With Non-Hodgkin Lymphoma Complicated by Superior Vena Cava Syndrome

Jessica S. Jang, RN, MSN, ACNP-BC, and Jeffrey S. Jang, BS

History OJ is a 40-year-old female with no significant past medical history. In January 2021, she noticed that her left neck veins were bulging, and she was diagnosed with a left internal jugular deep vein thrombosis. She was placed on apixaban and subsequently rivaroxaban and had a workup for th...


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