Current Issue


VOL 14 NO 2 • Mar 2023


This issue’s cover illustration depicts a patient with right parotid swelling with radiographically distant disease involving a paratracheal node and lung central hilum. PLAG1 in situ hybridization was performed on pulmonary specimens and found to be positive for translocation. Artwork by Alexandra Webber © 2023, DNA Illustrations, Inc., Asheville, North Carolina.


Editorial

The Importance of Professional Communities and Collaborations

Beth Faiman, PhD, MSN, APRN-BC, AOCN®, BMTCN, FAAN, FAPO

Picture this scenario. You are a provider who began a job in hematology at an outpatient community practice. A generally healthy 56-year-old patient with no past medical history of illness presents to you with complaints of bruising. They have not seen a provider in 15 years. You order appropriat...


Research and Scholarship

Integration of an APP-Led Supportive and Palliative Oncology Care Program: A Quality Improvement Project

Cecilia Motschenbacher, DNP, ARNP, FNP-C, ACHPN, AOCNP®, and Tanya Cohn, PhD, MEd, RN

Patients with advanced cancer have been found to demonstrate severe symptoms and low quality of life at diagnosis (Siemens et al., 2020). Advanced or metastatic cancer refers to disease that is unlikely to be cured or controlled with treatment. Treatment goals for this stage of illness are pallia...


Research and Scholarship

Characteristics of Distress and Support Group Participation in Caregivers of Older Allogeneic Hematopoietic Cell Transplantation Patients: A Single Institution Retrospective Review

Theresa A. Elko,(1) MPAS, PA-C, Samantha Brown,(2) MS, Stephanie Lobaugh,(2) MS, Sean Devlin,(2) PhD, Ann A. Jakubowski,(1,5) MD, PhD, Miguel-Angel Perales,(1,5) MD, Molly A. Maloy,(1) MS, Allison J. Applebaum,(3) PhD, Sergio A. Giralt,(1,5) MD, Lauren Levy,(1) MS, PA-C, Anne Schneider,(4) LMSW, and Richard J. Lin,(1,5) MD, PhD

Older adults represent a significant population of allogeneic hematopoietic cell transplant (allo-HCT) recipients; in 2018, 38% of allo-HCT recipients were 60 or older (D’Souza et al., 2020). Allo-HCT is a potentially curative therapy for hematologic malignancy, but one that comes with significan...


Review Article

Tisotumab Vedotin Safety and Tolerability in Clinical Practice: Managing Adverse Events

Courtney R. Arn,(1) APRN-CNP, Kimberly J. Halla,(2) MSN, FNP-C, and Sally Gill,(3) RN (Hons)

Cervical cancer is the fourth most frequently diagnosed and fourth most deadly cancer in women worldwide (Arbyn et al., 2020; Bray et al., 2018). Patients with recurrent or metastatic cervical cancer (r/mCC) experience a significant burden from disease-related symptoms, such as vaginal bleeding a...


Review Article

Physical Activity in Multiple Myeloma: A Review of the Current Literature

Michaela Hillengass,(1) RN, ACSM-CPT, Janine Joseph,(1) MS, MBA, Jane McCarthy, and Jens Hillengass,(1) MD, PhD

Being and staying active as a daily routine can be a significant challenge for patients diagnosed with multiple myeloma (MM). Not only do patients have to deal with the concomitant symptoms of the disease, but they also must face the limiting side effects of treatment. Fatigue, increased muscle t...


Grand Rounds

Using Pleomorphic Adenoma Gene 1 (PLAG1) to Distinguish Carcinoma of the Parotid Gland From Primary Lung Cancer: A Case Study

Avigayil East, DNP

Case Study A 40-year-old female never-smoker with no significant medical history presented with right-side facial swelling worsening over the course of 3 months, with progressive discomfort emanating from her right cheek and radiating to her right ear. An MRI of the skull base with and without co...


Prescriber's Corner

Teclistamab-cqyv: The First Bispecific T-Cell Engager Antibody for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma

Gwen Hua,(1) PharmD, BCOP, Ryan Scanlan,(2) PharmD Candidate, Rachael Straining,(1) PharmD, BCOP, and Daniel S. Carlson,(3) DO

Multiple myeloma (MM) is a plasma cell disorder characterized by the clonal proliferation of malignant plasma cells in the bone marrow with monoclonal protein in the serum and/or urine and associated organ dysfunction (Kyle & Rajkumar, 2004). Multiple myeloma is the second most common hematol...


Diagnostic Snapshot

Convergence of Hematology and Rheumatology: A Case Study

Mariangel Prieto, MSN, APRN, FNP-BC, AOCNP®

History MG is a 55-year-old male with a past medical history that is significant for type 2 diabetes mellitus, hypothyroidism, and auricular chondritis (Figure 1). Chief complaint He presented to the emergency room with reports of fevers up to 100.8°F, significant fatigue, and weakness. Diagnost...


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