Current Issue
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VOL 15 NO 4 • May/Jun 2024
This issue’s cover illustration depicts a patient receiving an infusion of amivantamab for advanced non–small cell lung cancer with EGFR exon 20 insertion mutations. Artwork by Alexandra Webber © 2024, DNA Illustrations, Inc., Asheville, North Carolina.EditorialBeth Faiman, PhD, MSN, APRN-BC, AOCN®, BMTCN, FAAN, FAPOAdvanced practitioners (APs) in hematology and oncology work in various practice settings. Many of us are well trained to diagnose and manage common oncologic emergencies, such as acute renal failure, severe anemia, hypercalcemia of malignancy, and sepsis. There is security in managing these acut...
Research and ScholarshipLindsay Dougherty,(1) CRNP, DNP, Whitney E. Lewis,(2) PharmD, BCOP, Meghan O’Neill,(1) CRNP, MSN, Amitabha Bhaumik,(3) PhD, Denise D’Andrea,(3) MD, and Andy L. Johnson,(3) PhDLung cancer is the second most common cancer in the world and the leading cause of cancer deaths (GLOBOCAN, 2020). Non–small cell lung cancer (NSCLC) makes up approximately 85% of all new lung cancer diagnoses (Minguet et al., 2016). Although patients with early-stage NSCLC can benefit from local...
Review ArticleCindy L. Cao, DNP, APRN, AGPCNP-C, AOCNP®, OCN®, BMTCN, Ashley Martinez, DNP, APRN, FNP-BC, AOCNP®, CBCN, CPHQ, NEA-BC, NPD-BC, and Joyce Dains, DrPH, JD, RN, FNP-BC, FNAP, FAANP, FAANChimeric antigen receptor (CAR) T-cell therapy is a treatment modality in which patients’ T lymphocytes are harvested, reengineered, and reinfused to display a receptor that later recognizes and helps to destroy malignant cells. CAR T-cell therapy was first approved in 2017 and revolutionized tre...
Review ArticleDebra M. Cole, EdD, PA-C, DFAAPA, Kaitlin Beane, PA-S, Madeleine Engel, PA-S, Madison Shaffer, PA-S, and Sarah Tartabini, PA-SCancer is a leading cause of death in the pediatric population, with 400,000 children diagnosed yearly (Tsai et al., 2014; Wong et al., 2021). Due to innovative advances, the overall survival rate for pediatric cancers in the United States is estimated to be approximately 83% (Raybin & Krajic...
Grand RoundsJillian Hunt, MSN, APRN, FNP-C, AOCNP®Case Study
A 61-year-old married, White male presented in late 2017 with a spot on his upper scalp. It had existed for approximately 1 year. About 3 to 4 months prior, it started to increase in size and bleed when the patient bumped the lesion, which prompted him to be seen by his dermatology pra...