Current Issue

VOL 15 NO 2 • Mar 2024

This issue’s cover illustration depicts a view of the heart opened to show the interior structures. The left ventricle exhibits myocarditis. The muscular wall is red and inflamed. There is decreased ability of the ventricle to pump efficiently. Activated T cells attach and injure the cardiomyocytes. Artwork by Alexandra Webber © 2024, DNA Illustrations, Inc., Asheville, North Carolina.


Burnout in Advanced Practitioners and the Benefit of Protected Time


Today, I learned an interesting fact. There is a diagnosis code to classify what many of us currently struggle with: burnout. The International Statistical Classification of Diseases and Related Health Problems (ICD-10) has a classification code for burnout, lack of relaxation and leisure, and mo...

Research and Scholarship

Burnout and Resiliency Among Advanced Practice Providers in Oncology Care

Abigail Baugh,(1) MPAS, PA-C, Victoria Reiser,(1) AG-ACDNP, BMTCN, OCN®, Jian Zhao,(2) PhD, RN, MS, Sara Jo Klein,(2) MS, BSN, RN, and Margaret Quinn Rosenzweig,(2) PhD, FNP-BC, AOCNP®, FAAN

Occupational exhaustion, or burnout, is prevalent and problematic among all health-care clinicians, including pharmacists, physicians, nurses, and advanced practice providers (Garcia et al., 2019). The syndrome was first recognized and studied among workers in human services and education in the ...

Research and Scholarship

A Comprehensive Bone Marrow Aspirate and Biopsy Educational Program Utilizing Task Trainers

Jessica Casselberry, DNP, ANP-BC, AOCNP®, and Jennifer Fisher, DNP, WHNP

Hematologic malignancies encompass acute or chronic leukemias; lymphomas; and plasma cell disorders. In 2023, it was estimated that approximately 184,720 people in the United States were diagnosed with leukemia, lymphoma, or myeloma (Leukemia & Lymphoma Society, 2023). The diagnosis of hemato...

Review Article

Risk Factors for Immune Checkpoint Inhibitor–Related Myocarditis: An Integrative Review

Sara M. Otto, MS, APRN, FNP-BC, AOCNP®, Ashely L. Martinez, DNP, APRN, FNP-BC, AOCNP®, CBCN, CPHQ, NEA-BC, and Joyce E. Dains, DrPH, JD, APRN, FNP-BC, FNAP, FAANP, FAAN

With the expanding use of immune checkpoint inhibitors (ICIs) to treat malignancy, side effects including myocarditis are commonly reported, further increasing the need for education on the prevention, diagnosis, and management of such toxicities. In 2011, the US Food and Drug Administration (FDA...

Grand Rounds

Intravenous Cetirizine Premedication to Mitigate Infusion-Related Reactions

Timothy Tyler,(1) PharmD, Erik Stojanoff,(2) PharmD, Joan Cannon,(2) PharmD, MBA, Jessie J. Um,(2) PharmD, BCPS, Stacia Young,(2) PharmD, BCOP, MBA, Jarrod P. Holmes,(3) MD, FACP, Lonnie D. Brent,(2) PharmD, and Nancy Martin,(2) MD, PharmD

CASE STUDY A 62-year-old woman with bilateral infiltrating ductal carcinoma (grade II estrogen receptor/progesterone receptor [ER/PR] positive, HER2/neu negative breast cancer) was administered intravenous (IV) diphenhydramine (DPH, Benadryl) 25 mg as a premedication for paclitaxel (Taxol) after ...

Practice Matters

The Ethics of Genetic Testing for Inherited Cancer-Predisposing Genes

Steven Sorscher,(1) MD, and Alisha T. DeTroye,(2) MMS, PA-C, DFAAPA

The National Comprehensive Cancer Network (NCCN) Hereditary Cancer panel publishes the standard-of-care guidelines in the United States that identify criteria for which individuals should be offered genetic testing for cancer-predisposing pathogenic germline variants (PGVs; NCCN, 2023). Genetic e...

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