Current Issue


VOL 13 NO 7 • Sep/Oct 2022


This issue’s cover illustration depicts the sagittal section through orbit showing intraocular cancer. A light-colored iris demonstrates color change along with a tumor arising from the melanocytes present in the lining of the retina. The background shows the tebentafusp-tebn mechanism of action as a drug molecule redirects T cells (on right) to target gp100-expressing uveal melanoma tumor cells (on left). Artwork by Alexandra Webber Baker © 2022, DNA Illustrations, Inc., Asheville, North Carolina.


Editorial

Insights Into the Publishing Process

Beth Faiman, PhD, MSN, APRN-BC, AOCN®, BMTCN, FAAN, FAPO

Writing for publication allows one to share ideas, thoughts, research, and practice patterns. A valuable tool to disseminate various types of information, peer-reviewed articles contribute to the body of literature and collective knowledge. As Editor-in-Chief of JADPRO, I receive many questions f...


Research and Scholarship

Management of Adverse Events in Early Clinical Trials by Advanced Practice Providers in the Outpatient Setting: The University of Texas MD Anderson Cancer Center Experience

Fedricker D. Barber (1), Erick Campbell (1), Yuko Yamamura (1), Clover J. Patterson (1), Audrey C. Hartnett (1), Holly Kinahan (1), Victoria A. Miller (1), Amanda L. Brink (1), Anna Poullard (1), Gabriele E. Urschel (1), Andre Brantley (1), Isabel G. Cepeda (1), Poonam Goswami (1), Sheena Charles (1), Shincy Philip (1), Sara Bresser (1), Sandra Musekiwa-Adjei (1), Nageli Perez (1), Hung Le (1), Penny Phillips (2), Vivek Subbiah (1), Funda Meric-Bernstam (1,3,4), and Ecaterina E. Dumbrava (1)

The process of clinical drug development classically has to follow three phases before regulatory (US Food and Drug Administration or European Medicines Agency) approval; however, there have been exceptions in which drugs were approved for tumor location–agnostic indications in the presence of co...


Research and Scholarship

The Impact of an Embedded Oncology Pharmacist in an Outpatient Oncology Center in the Treatment of Hematologic Malignancies

Denisse Mae Trinidad, PharmD, and Puja R. Patel, PharmD, BCOP

The Centers for Disease Control and Prevention and the US Surgeon General both acknowledge that increasing demands for access, safety, quality, and cost in the health-care system in the United States is a challenge, and that patient care services delivered by pharmacists can significantly contrib...


Review Article

Ultrasound Evaluation of Carotid Artery Intima-Media Thickness: Effective Early Marker of Carotid Artery Disease in Adult Head and Neck Cancer Patients After Neck Radiation?

Whitney Randolph, APRN, and Joyce E. Dains, DrPH, JD, APRN, FNP-BC, FNAP, FAANP

Radiation, either alone or with chemotherapy, is the recommended front-line treatment for many adult head and neck cancer (HNC) patients and has improved overall survival (National Comprehensive Cancer Network, 2021; Pulte & Brenner, 2010). Critical vascular structures, including the carotid ...


Review Article

The Role of Echocardiogram and Cardiac Rhythm Analysis for Early Detection of Cardiac Amyloidosis

Elizabeth Hubert, APRN, FNP-C, and Joyce E. Dains, DrPH, JD, APRN, FNP-BC, FNAP, FAANP

Amyloidosis refers to a family of diseases characterized by extracellular amyloid fibril deposition. Amyloid deposits result in significant dysfunction within the affected organs and soft tissues. The subtypes of amyloidosis most frequently encountered in clinical practice include light chain (AL...


Grand Rounds

Timely Genetic Testing and Therapy Management in Patients With gBRCA-Mutated Metastatic Breast Cancer Receiving Talazoparib

Ashley Martinez,(1) DNP, APRN, FNP-BC, AOCNP®, CBCN, CPHQ, NEA-BC, Tiffany Jones,(2) MSN, ACNP-BC, Joanne C. Ryan,(3) PhD, RN, Chad M. Barnett,(3) PharmD, BCOP, Elpitha L. Soussou,(3) PharmD, MBA, and Sarah Donahue,(4) MPH, NP, AOCNP®

Case Study Rozina is a 42-year-old premenopausal woman who presented to her primary care physician with worsening back pain over a few months that did not abate following physical therapy (Table 1). Her initial workup included an MRI of the thoracic spine that discovered a suspicious lesion at T6...


Practice Matters

Development of a Standardized Bone Marrow Procedure Training and Competency Toolkit for Advanced Practice Providers in a Large Community Oncology Practice

Katharine Lord,(1) PA-C, Sara Toth,(2) APRN, FNP-C, AOCNP®, AGN-BC, Jennifer Potter,(3) PA-C, Katherine Sellers,(4) PA-C, Monica White,(5) APRN, CNS-AH, ACNP-BC, AOCNP®, Anne Neugent,(4) APRN, FNP-C, and Tracy Martin,(4) APRN, ANP-C, AOCNP®, BMTCN, NursEd

Bone marrow aspiration and biopsy procedures are commonly used in oncology practice for the diagnosis and staging of hematologic/oncologic disease and evaluation of response to treatment. Trained providers, including advanced practice providers (APPs), perform this procedure in both inpatient and...


Prescriber's Corner

Tebentafusp-tebn: A Novel Bispecific T-Cell Engager for Metastatic Uveal Melanoma

Gwen Hua,(1) PharmD, Daniel Carlson,(2) DO, and Jacqueline R. Starr,(1) PharmD, BCOP

Uveal melanoma is the most common intraocular cancer in adults, representing approximately 3% to 5% of all melanomas (Jager et al., 2020). The annual incidence of uveal melanoma in Europe and the US is approximately 6 cases per million population per year (Jager et al., 2020). The incidence of uv...


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