Current Issue

VOL 14 NO 7 • Nov/Dec 2023

This issue’s cover illustration depicts the midsagittal section through the head with focus on the oropharynx and cancerous lesion at the base of the tongue. Graphic overlays make reference to HPV, specifically HPV-16 and the association with smoking to HPV-OPC. Artwork by Alexandra Webber © 2023, DNA Illustrations, Inc., Asheville, North Carolina.


JADPRO Live 2023: Shaping the Future of Oncology


The 2023 JADPRO Live conference was held in person from November 9 through 12 in sunny Orlando, Florida. It was wonderful reconnecting with advanced practitioners (APs) from around the country to catch up on the latest advances in hematology/oncology, along with their implications for advanced pr...

Research and Scholarship

Capecitabine for Salvage Treatment of Patients With Heavily Pretreated Human Papillomavirus–Associated Oropharynx Cancer With Distant Metastases

Anna C. Cooper, PA-C, Casey A. Fazer, PA-C, Ashish V. Chintakuntlawar, MBBS, PhD, Harry E. Fuentes Bayne, MD, MS, Patrick W. McGarrah, MD, and Katharine A. R. Price, MD

Head and neck squamous cell carcinoma (HNSCC) accounts for 4% of overall malignancies, with 66,920 patients diagnosed annually and 15,400 dying from their disease (Siegel et al., 2023). Despite a decrease in tobacco use, and the resultant decline in HNSCC overall, oropharyngeal cancer (OPC) has b...

Research and Scholarship

Clinical Utility of the 31-Gene Expression Profile Test on the Management of Cutaneous Melanoma by Nurse Practitioners and Physician Assistants

Renata Block,(1) MMS, PA-C, Deborah Patterson,(2) MMS, PA-C, Jennifer J. Siegel,(2) PhD, Brian Martin,(2) PhD, Ann P. Quick,(2) PhD, and Jillian Hunt,(3) MSN, APRN, FNP-C, AOCNP®

Cutaneous melanoma (CM) is the fifth most common malignancy in the United States, resulting in over 7,000 deaths annually (National Cancer Institute, 2023). The majority of patients with CM classified as low risk (stage I or II) according to American Joint Committee on Cancer (AJCC) staging guide...

Research and Scholarship

Characterization and Management of Adverse Reactions in Patients With Unresectable Hepatocellular Carcinoma Treated With Lenvatinib

Anna Jones,(1) FNP-C, Paola Degregorio,(2) PA-C, Max W. Sung,(3) MD, 
Zahra Ramji,(4) BSN, Min Ren,(5) PhD, and Ari D. Baron,(1) MD

In 2023, liver cancer accounted for 2.1% and 4.8% of estimated new cancer cases and cancer deaths in the United States, respectively (National Cancer Institute, 2023). Globally, in 2020, liver cancer was reported as 4.7% of new cancer cases but 8.3% of cancer deaths (Sung et al., 2021). Hepatocel...

Review Article

Impact of Fasting on Patients With Cancer: An Integrative Review

Samantha Thompson, MPH, MCHS, PA-C, Lydia T. Madsen, PhD, RN, AOCNS®, FNAP, and Angela Bazzell, DNP, APRN, FNP-BC, AOCNP®

Beyond the latest fad diet capturing the public’s attention, the practice of intermittent fasting has been advanced as a dietary intervention with the potential to positively impact cancer treatment by decreasing chemotherapy-related side effects and limiting tumor growth (Nencioni et al., 2018; ...

Review Article

Role of Preemptive Cytomegalovirus Hyperimmunoglobulin in Cytomegalovirus Viremia Following Stem Cell Transplant: An Integrative Review

Jaci Whittaker, MSN, APRN, FNP-BC, Ashley Martinez, DNP, APRN, FNP-BC, and Joyce E. Dains, DrPH, JD, APRN, FNP-BC, FANP, FAANP, FAAN

Cytomegalovirus (CMV) is a major cause of morbidity and mortality in immunocompromised patients following stem cell transplant (SCT; Styczynski, 2017). Cytomegalovirus remains latent after primary infection and can reactivate in a host during a time of immune suppression. Due to immune suppressio...

Grand Rounds

When Germline Genetic Testing Results Are Unclear: Highlighting Variants of Uncertain Significance

Patricia Kelly,(1) DNP, APRN, CNS, AGN-BC, AOCN®, Suzanne Mahon,(2) DNS, RN, AOCN®, AGN-BC, FAAN, and Patricia Friend,(3) PhD, APRN-CNS, AOCNS®, AGN-BC

Case Study LP is a 40-year-old premenopausal woman who was seen by a nurse practitioner for her well-woman exam. Because of her personal and family history of colon polyps, LP expressed interest in genetic testing to assess for hereditary cancer risk. LP’s health-care provider took a “shotgun” ap...

Practice Matters

Mitigating Burnout: Transition to a Condensed Workweek for Advanced Practice Providers in Infectious Diseases


Advanced practice providers (APPs) are an integral part of the health-care delivery system in the United States. They offer a cost-effective means of improving efficiency while maintaining high-quality patient care (American Association of Medical Colleges, 2021; Morgan et al., 2019). Advanced pr...


Thank You to Our Peer Reviewers!

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