Current Issue

VOL 9 • NO 7 NOV/DEC 2018

The cover illustration of this issue depicts a midsagittal view of the brain showing a close-up of the hypothalamus. The hypothalamus controls the circadian rhythms that guide the body’s natural sleeping and waking cycles. Highlighted are the suprachiasmatic nucleus (in yellow), which sets basic circadian rhythms, the preoptic (in lavender), which controls slow wake sleep, and the posterior hypothalamic nucleus (in blue), which promotes wakefulness. Overlaying ECG patterns show a waking state, deep sleep and REM sleep. Artwork by Alexandra Webber Baker, ©2018, DNA Illustrations, Inc., Asheville, North Carolina.


Human Papillomavirus and Cancer

Pamela Hallquist Viale, RN, MS, CNS, ANP

Earlier this November, the sixth annual JADPRO Live meeting was held in sunny Hollywood, Florida. The weather was fantastic, we had the most attendees ever (over 1,400), and the sessions were exciting, informative, and relevant to our practice as advanced practitioners! If you weren’t able to joi...

Review Article

Potential of Biosimilars to Increase Access to Biologics: Considerations for Advanced Practice Providers in Oncology

Sara M. Tinsley,(1) PhD, ARNP, AOCN®, Carolyn Grande,(2) CRNP, AOCNP®, Karin Olson,(3) PhD, PA-C, Leah Plato,(4) PA-C, MPH, CCRP, and Ira Jacobs,(5) MD, JD, MBA, FACS

Due to their structure, chemically derived drugs such as small molecules can be readily characterized and produced with high purity on a large scale (Crommelin et al., 2005; Daller, 2016; Dombrowski, 2013; Kuhlmann & Covic, 2006; Schellekens, 2009). In contrast, biologic drugs are large compo...

Translating Research Into Practice

The Stepped-Wedge Trial Design: Paving the Way for Cancer Care Delivery Research

Ya-Huei Li, PhD, Elizabeth Mullette, RN, MSN, and Jeannine M. Brant, PhD, APRN, AOCN®, FAAN

Cancer care delivery research (CCDR) is defined as “the multidisciplinary field of scientific investigation that studies how social factors, financing systems, organizational structures and processes, health technologies, and health-care provider and patient behaviors affect access to cancer care...

Practice Matters

Cognitive Behavioral Therapy for Sleep in Cancer Patients: Research, Techniques, and Individual Considerations

Laura Melton, PhD, ABPP

Sleep is a necessary component of life; humans spend about one-third of their lives asleep (Dresler et al., 2014). Sleep helps restore the body, plays a role in temperature regulation, and influences the immune system and hormones (Hearson & Sawatzky, 2008; Van Someren et al., 2015). Sleep dr...

Prescriber's Corner

Trametinib: A Targeted Therapy in Metastatic Melanoma

Brianna Hoffner, MSN, ANP-BC, AOCNP®, and Katherine Benchich, MSN, NP-C, AOCNP®

Melanoma accounts for just 1% of all skin cancers, but the majority of skin cancer deaths (American Cancer Society, 2018). The incidence of melanoma has increased significantly over the past 30 years, with a 3% increase per year between 2005 and 2014 among those age 50 and older (American Cancer ...

Prescriber's Corner

Neratinib for the Treatment of Early-Stage HER2-Positive Breast Cancer

Jennifer Miles, PharmD, and Yahsin White, PharmD

Breast cancer is the most common type of cancer and the second leading cause of cancer death in women. The American Cancer Society (2018) estimates that about 266,120 new cases of invasive breast cancer and 63,960 new cases of carcinoma in situ will be diagnosed this year in the United States. It...

Tools and Technology

Collaboration Leads to Oral Chemotherapy Education

Ashley E. Glode,(1) PharmD, BCOP, Lisa Holle,(2) PharmD, BCOP, FHOPA, Josh Nubla,(3) PharmD, Mike Minjock,(4) Nancy Egerton,(3) PharmD, BCOP, Kris LeFebvre,(4) MSN, RN, AOCN®, Michael Reff,(3) RPh, MBA, and David DeRemer,(5) PharmD, BCOP, FCCP

Providing comprehensive chemotherapy education to patients in a busy clinical practice setting can be challenging. Potential barriers to providing patient education include work overload, low priority, difficulty in communication, insufficient knowledge and skills, and lack of comprehensive tools...

Diagnostic Snapshot

Diagnostic Snapshot: Painful Nodules and Recurrent Fever in a Patient With Acute Lymphoblastic Leukemia

Alexis C. Geppner, MLS(ASCP), PA-C

Oncologic History Mr. S is a 39-year-old Hispanic male with a diagnosis of Philadelphia chromosome–negative acute lymphoblastic leukemia, diagnosed in October 2015 with a hyperdiploid karyotype and mutations in TP53 and NRAS. He was enrolled on a clinical trial with Hyper-CVAD (cyclophosphamide,...


Thank You to Our Peer Reviewers!

In this last issue of the year, we would like to acknowledge everyone who completed peer reviews for JADPRO in the past year. Our reviewers, who are from a wide variety of oncology specialties, dedicate their expertise and time to provide insightful feedback on submitted manuscripts. We hope tha...

Meeting Abstract

Abstracts from JADPRO Live 2018

JL601. Advanced Practice Nurse Orientation Sue Schwartz, MSN, RN, APN, AOCNP®, and Renee Kurz, DNP, FNP-BC, AOCNP; Rutgers Cancer Institute of NJ Objective: The Rutgers Cancer Institute of New Jersey is New Jersey’s only NCI-designated cancer center. The mission and vision of the center is to p...



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